Idrossiclorochina e clorochina dosaggio
Do not double doses. The dosage of chloroquine phosphate is often expressed in terms of equivalent chloroquine base. In infants and children the dosage is preferably calculated by body weight. Pediatric Dose: The weekly suppressive dosage is 5 mg calculated as base, per kg of body weight, but should not exceed the adult dose regardless of weight. If circumstances permit, suppressive therapy should begin two weeks prior to exposure.
The suppressive therapy should be continued for eight weeks after leaving the endemic area. For Treatment of Acute Attack. This represents a total dose of 2. The dosage for adults of low body weight and for infants and children should be determined as follows: First dose: 10 mg base per kg but not exceeding a single dose of mg base. Second dose: 6 hours after first dose 5 mg base per kg but not exceeding a single dose of mg base. Third dose: 24 hours after first dose 5 mg base per kg.
Fourth dose: 36 hours after first dose 5 mg base per kg. For radical cure of vivax and malariae malaria concomitant therapy with an 8-aminoquinoline compound is necessary.
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Extraintestinal Amebiasis: Adults,1 g mg base daily for two days, followed by mg mg base daily for at least two to three weeks. Treatment is usually combined with an effective intestinal amebicide. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed. If you will be taking chloroquine for a long time, it is very important that your doctor check you at regular visits for any blood problems or muscle weakness that may be caused by chloroquine.
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In addition, check with your doctor immediately if blurred vision, difficulty in reading, or any other change in vision occurs during or after treatment. Your doctor may want you to have your eyes checked by an ophthalmologist eye doctor. If your symptoms do not improve within a few days or if they become worse, check with your doctor. Make sure you know how you react to chloroquine before you drive, use machines, or do anything else that could be dangerous if you are not able to see well.
Chloroquine may cause blurred vision, difficulty in reading, or other change in vision. It may also cause some people to become lightheaded. If these reactions are especially bothersome, check with your doctor. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur.
Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. There are no adequate and well-controlled studies evaluating the safety and efficacy of chloroquine in pregnant women. Usage of chloroquine during pregnancy should be avoided except in the suppression or treatment of malaria when in the judgment of the physician the benefit outweighs the potential risk to the fetus.
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